Relationship between serum levels of chromium and iron with transferrin and albumin levels as carrier proteins in diabetic patients with atherosclerosis

Backgrounds: Type 2 diabetes mellitus is one of the most common metabolic diseases in the world, resulting in complete or partial deficiency or resistance to insulin action. In this study, the association between serum levels of chromium and iron with serum levels of their carriers, transferrin and albumin in diabetic patients with atherosclerosis was investigated. Materials and methods: In this study, 5 cc blood samples was taken from 30 diabetic patients with atherosclerosis and 30 healthy subjects. Serum chromium and iron levels of serum were measured by atomic absorption method and spectrophotometric method, respectively. Finally, the data were analyzed using SPSS (version 23). Results: The results showed that serum albumin level in patients was slightly increased compared to healthy subjects, but there was a significant difference (P-value = 0.444). In the patient group, the correlation coefficient of iron and transferrin (R2 = 0.022) was higher than the correlation coefficient of iron and albumin (R² = 0.0053) and statistically significant (P-value = 0.05). Conclusion: It can be concluded that in diabetics suffering from atherosclerosis, iron and albumin levels were higher than chromium and transferrin, but further research is needed. We hope that by studying these factors and proteins, this treatment gets more appropriate than other treatments for Diabetic patients with atherosclerosis.